Infections of the resp tract, middle ear (otitis media), paranasal sinuses (sinusitis) especially caused by gm -ve organisms including Pseudomonas or Staphylococcus, eyes, kidneys, urinary tract, genital organs including adnexitis, gonorrhoea & prostatitis; abdominal cavity (eg, bacterial infections of GIT, biliary tract, peritonitis); skin & soft tissue, bones & joints, septicaemia.
Dosage/Direction for Use
AdultResp tract infections 250-500 mg bd. Acute uncomplicated UTI 250 mg once-bd. Cystitis in pre-menopausal women 250 mg as single dose. Complicated UTI 250-500 mg bd. Acute gonorrhoea 250 mg as single dose. Other infections 500 mg bd. Severe, life-threatening infections 750 mg bd. Surgical prophylaxis 750 mg as single dose given 60-90 min pre-op.
Administration
May be taken with or without food: May be taken w/ meals to minimise GI discomfort. Do not take w/ antacids, Fe or dairy products. Ensure adequate fluid intake.
Contraindications
Hypersensitivity to quinolones. Pregnancy & lactation. Childn, adolescents.
Special Precautions
Epilepsy, history of CNS disorders (eg, lower convulsion threshold, previous history of convulsion, reduced cerebral blood flow, altered brain structure or stroke). G6PD deficiency, myasthenia gravis. Maintain adequate hydration. Avoid UV exposure. May impair ability to drive or operate machinery. Renal or hepatic impairment. Elderly.
Sign Out
